Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825414 | 0.93 | LMNA (0.63) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL673623 | 0.91 | LMNA (0.61) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL149160 | 0.91 | LMNA (0.61) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL638764 | 0.91 | LMNA (0.61) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL672047 | 0.91 | LMNA (0.61) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL8718249 | 0.91 | LMNA (0.61) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL1386528 | 0.86 | LMNA (0.57) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL864165 | 0.85 | LMNA (0.52) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL4018453 | 0.85 | LOXL2 (0.56) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL1500719 | 0.84 | LMNA (0.55) | LMNAKDM4EALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | RNASEH1, CTSH, RNASE1 | LMNA 2574/4885KDM4E 104/4885ALDH1A1 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.