Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235373 | 0.91 | HSD17B10 (0.74) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6686477 | 0.89 | CYP2C9 (0.63) | HSD17B10MAPK1CYP2C9NR1I2L3MBTL1 | |
| SCHEMBL6236195 | 0.88 | MAPK1 (0.68) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6693292 | 0.87 | CYP2C9 (0.70) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6681450 | 0.85 | CYP2C9 (0.66) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6242538 | 0.85 | MAPK1 (0.64) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6238653 | 0.83 | CYP2C9 (0.62) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6235524 | 0.82 | MAPK1 (0.67) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6685735 | 0.82 | MAPK1 (0.57) | HSD17B10MAPK1CYP2C9NR1I2KDM4E | |
| SCHEMBL6235728 | 0.81 | HSD17B10 (0.68) | HSD17B10MAPK1CYP2C9NR1I2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |