Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259170 | 0.84 | CA12 (0.75) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6670346 | 0.77 | CA12 (0.74) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18292676 | 0.76 | KMT2A (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23928504 | 0.74 | CA12 (0.75) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4501557 | 0.72 | ALDH1A1 (0.82) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2031958 | 0.72 | PARP1 (0.59) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL28210218 | 0.72 | PARP1 (0.59) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4903548 | 0.71 | ALDH1A1 (0.60) | CA12CA1CA2CA9ALDH1A1 | |
| Propionic Acid SCHEMBL28500081 | 0.71 | CA12 (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL976547 | 0.71 | AURKA (0.74) | CA12CA9ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |