Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361248 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP3A4CYP2C9MEN1 | |
| SCHEMBL17345637 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL512637 | 0.81 | KMT2A (0.46) | CYP3A4CYP2C9MEN1KMT2AHPGD | |
| SCHEMBL29924605 | 0.81 | KMT2A (0.46) | CYP3A4CYP2C9MEN1KMT2AHPGD | |
| SCHEMBL1511092 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4656411 | 0.80 | ALDH1A1 (0.54) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6686448 | 0.79 | FFAR4 (0.51) | SMN1; SMN2POLB | |
| SCHEMBL27176866 | 0.78 | CYP4F2 (0.66) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8585798 | 0.78 | CYP4F2 (0.57) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL901696 | 0.78 | CYP4F2 (0.53) | CYP4F2CYP4A11CYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071389-A2 | NON-STEROIDAL INFALMMATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |