Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924605 | 1.00 | KMT2A (0.46) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL18641931 | 0.86 | KMT2A (0.57) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL16731569 | 0.85 | KMT2A (0.49) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL8361248 | 0.85 | CYP4F2 (0.50) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL31441299 | 0.84 | KMT2A (0.57) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL1525187 | 0.84 | ERCC1 (0.46) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL706766 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1HPGDALDH1A1HTT | |
| SCHEMBL707398 | 0.84 | KMT2A (0.57) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL10258195 | 0.84 | NLRP3 (0.43) | KMT2AALDH1A1TDP1CYP2C9PKM | |
| SCHEMBL15011980 | 0.83 | EGFR (0.52) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062401-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | NEUMORA THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-12371414-B2 | Methods of treating neurological disorders | Neumora Therapeutics, Inc. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20240294492-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | Neumora Therapeutics, Inc. | 2024-09-05 | — | — | US | disclosed |
| US-20240246928-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | Neumora Therapeutics, Inc. | 2024-07-25 | — | — | US | disclosed |
| WO-2024119067-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | Neumora Therapeutics, Inc. (US) | 2024-06-06 | — | — | WO | disclosed |
| US-11993580-B1 | Methods of treating neurological disorders | Neumora Therapeutics, Inc. (US) | 2024-05-28 | — | — | US | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| EP-0885885-B1 | PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6242634-B1 | OF HERBICIDES, HALOPHENYL COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6100257-A | 2-HALOALKYL,3-(HALOALKYL, ALKENYL, OR ALKYNYL),5-(SUBSTITUTED PHENYL OR HETEROCYCLE),6-ALKYL-PYRIMIDIN-4-ONE COMPOUNDS OF GIVEN STRUCTURE; USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |
| CN-1198742-A | Pyrimidin-4-one derivatives, their use as herbicides, intermediates for their production and process for producing these compounds | SUMITOMO CHEMICAL CO (JP) | 1998-11-11 | — | — | CN | disclosed |
| EP-0850229-A1 | PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997006150-A1 | PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993580-B1 | Methods of treating neurological disorders | SMN1; SMN2, CLN6, PMP22 | KMT2A 3345/4885MEN1 1283/4885HPGD 851/4885 |
| US-20240246928-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | SMN1; SMN2, CLN6, PMP22 | KMT2A 3345/4885MEN1 1283/4885HPGD 851/4885 |
| US-20260062401-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | HCN2, HCN3, HCN1 | KMT2A 2170/4885MEN1 911/4885HPGD 3761/4885 |
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | BTK, SRC, YES1 | KMT2A 1866/4885MEN1 306/4885HPGD 4855/4885 |
| US-20240294492-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | SMN1; SMN2, CLN6, PMP22 | KMT2A 3283/4885MEN1 1319/4885HPGD 823/4885 |
| US-12371414-B2 | Methods of treating neurological disorders | SMN1; SMN2, CLN6, PMP22 | KMT2A 3345/4885MEN1 1283/4885HPGD 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.