Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663920 | 0.83 | RXRA (0.38) | HMGCRRARGRXRAPPARGMAPT | |
| SCHEMBL5668478 | 0.83 | RARG (0.39) | RARGRXRAPPARGTNFRSF1APTPN1 | |
| SCHEMBL6683401 | 0.78 | RXRA (0.35) | HMGCRRARGRXRAPPARGTNFRSF1A | |
| SCHEMBL6680912 | 0.77 | RXRA (0.41) | RARGRXRAPPARGMAPTTNFRSF1A | |
| SCHEMBL5662542 | 0.77 | RXRA (0.41) | RARGRXRAPPARGMAPTTNFRSF1A | |
| SCHEMBL9228303 | 0.76 | HMGCR (0.51) | HMGCRTNFRSF1A | |
| SCHEMBL6672264 | 0.75 | RXRA (0.43) | RARGRXRAPPARGTNFRSF1A | |
| SCHEMBL5663415 | 0.74 | RXRA (0.38) | RARGRXRAPPARGTNFRSF1A | |
| SCHEMBL5667374 | 0.74 | RXRA (0.38) | RARGRXRAPPARGTNFRSF1A | |
| SCHEMBL5663900 | 0.74 | RXRA (0.38) | RARGRXRAPPARGTNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026243-A2 | THERAPEUTIC USES OF LINEAR KETOPHOSPHONATES | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |