Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686703 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AITGB2 | |
| SCHEMBL6686710 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AITGB2 | |
| SCHEMBL6687419 | 0.87 | LMNA (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAFBP1 | |
| SCHEMBL6687420 | 0.87 | LMNA (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAFBP1 | |
| SCHEMBL6685070 | 0.84 | GPR119 (0.42) | MAPTLMNAFBP1MAOB | |
| SCHEMBL6685065 | 0.84 | GPR119 (0.42) | MAPTLMNAFBP1MAOB | |
| SCHEMBL6685058 | 0.84 | GPR119 (0.42) | MAPTLMNAFBP1MAOB | |
| SCHEMBL6690504 | 0.82 | MAOB (0.42) | MAOB | |
| SCHEMBL6690512 | 0.82 | MAOB (0.42) | MAOB | |
| SCHEMBL6690510 | 0.82 | MAOB (0.42) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |