Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP18 | Q9UMW8 | 1/20 | 0.38 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687420 | 1.00 | LMNA (0.47) | LMNAALDH1A1MAPTPTPN1HTT | |
| SCHEMBL6686710 | 0.87 | MAPT (0.48) | LMNAALDH1A1MAPTSMN1; SMN2MAOB | |
| SCHEMBL6686703 | 0.87 | MAPT (0.48) | LMNAALDH1A1MAPTSMN1; SMN2MAOB | |
| SCHEMBL6686706 | 0.87 | MAPT (0.48) | LMNAALDH1A1MAPTSMN1; SMN2MAOB | |
| SCHEMBL6690143 | 0.84 | GPR119 (0.41) | LMNAMAPTPTPN1SMN1; SMN2KMT2A | |
| SCHEMBL6690141 | 0.84 | GPR119 (0.41) | LMNAMAPTPTPN1SMN1; SMN2KMT2A | |
| SCHEMBL6687262 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1PTPN1SMN1; SMN2MAOB | |
| SCHEMBL6687260 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1PTPN1SMN1; SMN2MAOB | |
| SCHEMBL6685702 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AMAOB | |
| SCHEMBL6685695 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |