Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678084 | 0.89 | MAPT (0.72) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6688828 | 0.85 | MEN1 (0.67) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6684407 | 0.84 | KDM4E (0.70) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6676970 | 0.84 | MAPT (0.66) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6679138 | 0.83 | MAPT (0.64) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6683017 | 0.81 | MAPT (0.68) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6680339 | 0.81 | ADORA3 (0.66) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6683268 | 0.81 | MAPT (0.62) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6683414 | 0.81 | MAPT (0.62) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6681967 | 0.79 | MEN1 (0.66) | MEN1KMT2AMAPTTSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |