Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689892 | 0.85 | NR3C1 (0.43) | NR3C1KDM5AKDM4CKDM5B | |
| SCHEMBL15673547 | 0.82 | NR3C1 (0.44) | NR3C1KDM5AKDM4CKDM5BKMT2A | |
| SCHEMBL6684521 | 0.82 | KDM5A (0.47) | NR3C1KDM5AKDM4CKDM5BKMT2A | |
| SCHEMBL6688420 | 0.82 | HDAC9 (0.41) | NR3C1 | |
| SCHEMBL808956 | 0.79 | NR3C1 (0.51) | NR3C1 | |
| SCHEMBL5138499 | 0.79 | KDM1A (0.50) | NR3C1KMT2AMEN1AKR1B1 | |
| SCHEMBL6925659 | 0.75 | NR3C1 (0.40) | NR3C1KDM5AKDM4CKDM5B | |
| SCHEMBL24483733 | 0.74 | KMT2A (0.41) | KDM5AKDM4CKDM5BKMT2AMEN1 | |
| SCHEMBL5547903 | 0.73 | SIGMAR1 (0.47) | NR3C1KMT2AMEN1 | |
| SCHEMBL23385700 | 0.73 | KDM1A (0.49) | NR3C1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071389-A2 | NON-STEROIDAL INFALMMATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |