Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685637 | 0.85 | CTSK (0.41) | CTSKPOLB | |
| SCHEMBL5404868 | 0.85 | CTSK (0.36) | CTSKALDH1A1 | |
| SCHEMBL5842740 | 0.74 | HTT (0.34) | CYP2C19HTT | |
| SCHEMBL6686843 | 0.69 | CTSS (0.45) | CTSKALDH1A1MAPTPOLB | |
| SCHEMBL5841920 | 0.67 | CTSS (0.49) | CTSKMAPT | |
| SCHEMBL5841917 | 0.66 | PARP10 (0.39) | ALDH1A1MAPTPOLBHTT | |
| SCHEMBL4796236 | 0.66 | MAPT (0.45) | CTSKALDH1A1MAPTPOLBHTT | |
| SCHEMBL3154827 | 0.65 | NAMPT (0.40) | CYP2C19 | |
| SCHEMBL3019566 | 0.65 | CTSS (0.39) | CTSK | |
| SCHEMBL6687352 | 0.64 | MAPT (0.45) | ALDH1A1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |