Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986913 | 0.85 | GABRR1 (0.46) | GABRR1KDM4ELMNAHTR2C | |
| SCHEMBL13096842 | 0.79 | TDP1 (0.39) | — | |
| SCHEMBL3169639 | 0.77 | ARG1 (0.32) | KDM4ELMNAAPPARG1 | |
| SCHEMBL16853135 | 0.76 | GABRR1 (0.58) | GABRR1KDM4ELMNAHTR2C | |
| SCHEMBL393044 | 0.75 | LMNA (0.50) | GABRR1LMNA | |
| SCHEMBL16853138 | 0.73 | GABRR1 (0.55) | GABRR1KDM4ELMNAHTR2C | |
| SCHEMBL16853123 | 0.73 | GABRR1 (0.55) | GABRR1KDM4ELMNAHTR2C | |
| SCHEMBL16853370 | 0.73 | GABRR1 (0.55) | GABRR1KDM4ELMNAHTR2C | |
| SCHEMBL5842384 | 0.73 | ARG1 (0.31) | ARG1 | |
| SCHEMBL14009835 | 0.73 | PAOX (0.46) | LMNAARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004094465-A2 | SYNTHETIC MOLECULES THAT MIMIC CHEMOKINES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS OFFICE OF TECHNOLOGY MANAGEMENT UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (US) | 2004-11-04 | — | — | WO | disclosed |