Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315988 | 0.98 | CTRB1 (0.42) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL18315990 | 0.98 | CTRB1 (0.42) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL6135405 | 0.89 | AURKA (0.40) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL10001904 | 0.85 | AURKA (0.47) | CTRB1AURKAAURKBCYP1A2MEN1 | |
| SCHEMBL433199 | 0.85 | AURKA (0.44) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL30349926 | 0.85 | AURKA (0.44) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL11528264 | 0.83 | AURKA (0.46) | CTRB1AURKAAURKBCYP1A2MEN1 | |
| SCHEMBL6535450 | 0.83 | AURKA (0.38) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL28048029 | 0.82 | AURKA (0.42) | CTRB1AURKAAURKBCYP1A2CYP2D6 | |
| SCHEMBL3822788 | 0.82 | AURKA (0.42) | CTRB1AURKAAURKBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111133312-A | Methods for diagnosing and treating lung cancer | 萨维塞尔诊断有限公司 | 2020-05-08 | — | — | CN | claimed |
| EP-3060607-B1 | SOL-GEL BASED MATRIX | UNIV COPENHAGEN (DK) | 2018-05-30 | — | — | EP | claimed |
| CN-117460818-A | Nanometer vesicle reactor and preparation method thereof | 基础科学研究院 | 2024-01-26 | — | — | CN | disclosed |
| CN-111133312-A | Methods for diagnosing and treating lung cancer | 萨维塞尔诊断有限公司 | 2020-05-08 | — | — | CN | disclosed |
| WO-2018178992-A9 | METHOD AND SYSTEM FOR SEPARATING BIOMOLECULES FROM A MIXTURE CONTAINING SAME | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-06-20 | — | — | WO | disclosed |
| CN-105492502-B | Organic phosphor functionalized nano-particles and composition comprising it | 伦斯莱尔工艺研究院 | 2018-09-21 | — | — | CN | disclosed |
| CN-108028302-A | Rubbery materials for immobilizing proteins and their use in lighting, diagnostics and biocatalysis | IMDEA材料基金会 | 2018-05-11 | — | — | CN | disclosed |
| WO-2004072267-A2 | ENZYMES | INCYTE CORPORATION (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004003162-A2 | ENZYMES | INCYTE CORPORATION (US) | 2004-01-08 | — | — | WO | disclosed |
| WO-2003093439-A2 | ENZYMES | INCYTE CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
| EP-0667318-B1 | Fluorescent tracer in sludge dewatering | NALCO CHEMICAL CO (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0667318-A1 | Fluorescent tracer in sludge dewatering | NALCO CHEMICAL COMPANY (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5413719-A | To determine optimum amount of polyelectrolyte | NALCO CHEMICAL COMPANY (US) | 1995-05-09 | — | — | US | disclosed |