Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.56 |
| ▸ | CTSL | P07711 | 14/20 | 0.56 |
| ▸ | CTSK | P43235 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685381 | 0.85 | CTSL (0.75) | CTSSCTSLCTSK | |
| SCHEMBL5842483 | 0.85 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL5842487 | 0.85 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL5841146 | 0.84 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL5841153 | 0.84 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL6692650 | 0.81 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL6691086 | 0.81 | CTSS (0.59) | CTSSCTSLCTSK | |
| SCHEMBL6690169 | 0.81 | CTSL (0.73) | CTSSCTSLCTSK | |
| SCHEMBL6690835 | 0.79 | CTSL (0.55) | CTSSCTSLCTSKMEN1NPC1 | |
| SCHEMBL5843021 | 0.78 | CTSL (0.73) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |