Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.55 |
| ▸ | CTSS | P25774 | 13/20 | 0.55 |
| ▸ | CTSK | P43235 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843021 | 0.84 | CTSL (0.73) | CTSLCTSSCTSK | |
| SCHEMBL5843014 | 0.84 | CTSL (0.73) | CTSLCTSSCTSK | |
| SCHEMBL6690841 | 0.84 | CTSL (0.65) | CTSLCTSSCTSK | |
| SCHEMBL6693130 | 0.81 | CTSL (0.61) | CTSLCTSSCTSK | |
| SCHEMBL6687754 | 0.80 | CTSL (0.69) | CTSLCTSSCTSK | |
| SCHEMBL6687230 | 0.79 | CTSS (0.56) | CTSLCTSSCTSKLMNAHTT | |
| SCHEMBL6688735 | 0.79 | CTSL (0.71) | CTSLCTSSCTSK | |
| SCHEMBL6685376 | 0.79 | CTSL (0.68) | CTSLCTSSCTSK | |
| SCHEMBL6687707 | 0.79 | CTSL (0.58) | CTSLCTSSCTSK | |
| SCHEMBL6685689 | 0.79 | CTSL (0.70) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |