Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687232 | 1.00 | MAOB (0.51) | MAOBMAOASCN9ACTSDHRH3 | |
| SCHEMBL6685490 | 0.89 | ATM (0.48) | CTSDNPC1PKMRAB9A | |
| SCHEMBL6685493 | 0.89 | ATM (0.48) | CTSDNPC1PKMRAB9A | |
| SCHEMBL6687574 | 0.88 | MAOB (0.47) | MAOBMAOASCN9ACTSDNPC1 | |
| SCHEMBL6687571 | 0.88 | MAOB (0.47) | MAOBMAOASCN9ACTSDNPC1 | |
| SCHEMBL6687466 | 0.85 | CTSD (0.56) | CTSDNPC1PKMRAB9A | |
| SCHEMBL6687470 | 0.85 | CTSD (0.56) | CTSDNPC1PKMRAB9A | |
| SCHEMBL6693067 | 0.85 | MAOB (0.45) | MAOBMAOASCN9ANPC1PKM | |
| SCHEMBL6693062 | 0.85 | MAOB (0.45) | MAOBMAOASCN9ANPC1PKM | |
| SCHEMBL6690012 | 0.84 | SMN1; SMN2 (0.48) | MAOBMAOASCN9ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |