Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.53 |
| ▸ | CTSL | P07711 | 12/20 | 0.53 |
| ▸ | CTSK | P43235 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689172 | 0.85 | CTSS (0.61) | CTSSCTSLCTSK | |
| SCHEMBL6691132 | 0.83 | CTSS (0.69) | CTSSCTSLCTSKMAPTRAB9A | |
| SCHEMBL6685381 | 0.82 | CTSL (0.75) | CTSSCTSLCTSK | |
| SCHEMBL6685236 | 0.82 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL6691086 | 0.81 | CTSS (0.59) | CTSSCTSLCTSK | |
| SCHEMBL5842763 | 0.81 | CTSS (0.72) | CTSSCTSLCTSK | |
| SCHEMBL5842769 | 0.81 | CTSS (0.72) | CTSSCTSLCTSK | |
| SCHEMBL6687973 | 0.81 | EPHX2 (0.50) | CTSSCTSLCTSKNPC1RAB9A | |
| SCHEMBL5843852 | 0.81 | CTSS (0.78) | CTSSCTSLCTSK | |
| SCHEMBL5843860 | 0.81 | CTSS (0.78) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |