Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.69 |
| ▸ | CTSL | P07711 | 9/20 | 0.69 |
| ▸ | CTSK | P43235 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687243 | 0.83 | CTSS (0.53) | CTSSCTSLCTSKRAB9AMAPT | |
| SCHEMBL5843384 | 0.82 | CTSS (0.85) | CTSSCTSLCTSK | |
| SCHEMBL5843387 | 0.82 | CTSS (0.85) | CTSSCTSLCTSK | |
| SCHEMBL6689172 | 0.81 | CTSS (0.61) | CTSSCTSLCTSK | |
| SCHEMBL6685381 | 0.80 | CTSL (0.75) | CTSSCTSLCTSK | |
| SCHEMBL6692650 | 0.78 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL6691086 | 0.77 | CTSS (0.59) | CTSSCTSLCTSK | |
| SCHEMBL6693346 | 0.77 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL6690368 | 0.75 | CTSS (0.58) | CTSSCTSLCTSKALDH1A1KMT2A | |
| SCHEMBL6690169 | 0.75 | CTSL (0.73) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |