Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693815 | 0.80 | MAPT (0.44) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL126109 | 0.74 | MAPT (0.57) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL11696288 | 0.73 | MAPT (0.47) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL11695656 | 0.73 | MAPT (0.32) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL11697951 | 0.70 | MAPT (0.44) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11691065 | 0.70 | DTYMK (0.42) | MAPTALDH1A1CYP3A4KMT2APOLB | |
| SCHEMBL11857762 | 0.70 | NOS3 (0.38) | MAPTALDH1A1KDM4ECYP3A4CYP1A2 | |
| SCHEMBL11697167 | 0.70 | MAPT (0.44) | MAPTALDH1A1GAAKMT2APOLB | |
| SCHEMBL4527628 | 0.67 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11697414 | 0.66 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824974-B2 | Electronic detection of biological molecules using thin layers | GENORX, INC. | 2004-11-30 | — | — | US | disclosed |