SCHEMBL668745

SCHEMBL668745

O=c1ccc2cc(F)c(O)c(F)c2o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 7/20 0.61
▸ MGAM O43451 5/20 0.61
▸ SI P14410 5/20 0.61
▸ MGAM2 Q2M2H8 5/20 0.61
▸ MCL1 Q07820 9/20 0.55
▸ KDM4E B2RXH2 4/20 0.55
▸ ALDH1A1 P00352 4/20 0.55
▸ HPGD P15428 4/20 0.55
▸ HSD17B10 Q99714 4/20 0.55
▸ MAPT P10636 3/20 0.55
▸ ALOX15 P16050 3/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ LMNA P02545 2/20 0.55
▸ CYP1A2 P05177 2/20 0.55
▸ CYP3A4 P08684 2/20 0.55
▸ PRKD3 O94806 1/20 0.55
▸ EGFR P00533 1/20 0.55
▸ PRKCG P05129 1/20 0.55
▸ PRKCB P05771 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363321 1.00 GAA (0.61) GAAMGAMSIMGAM2MCL1
SCHEMBL27739742 0.83 GAA (0.53) GAAMGAMSIMGAM2MCL1
SCHEMBL15288853 0.78 GPR35 (0.41) GAAMGAMSIMGAM2KDM4E
SCHEMBL4658019 0.77 GAA (0.75) GAAMGAMSIMGAM2MCL1
SCHEMBL8571050 0.75 MET (0.51) GAAMGAMSIMGAM2MCL1
SCHEMBL15842620 0.75 MCL1 (0.48) GAAMGAMSIMGAM2MCL1
SCHEMBL8571187 0.73 GAA (0.53) GAAMGAMSIMGAM2MCL1
SCHEMBL12814095 0.73 CA9 (0.72) GAAMGAMSIMGAM2MCL1
SCHEMBL17696461 0.72 HSD17B3 (0.42) GAAMCL1KDM4EALDH1A1HPGD
Daphnetin SCHEMBL29612544 0.71 MCL1 (1.00) GAAMGAMSIMGAM2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260010026-A1 ENGINEERED LIQUID CRYSTAL SHUTTER AS A DYNAMIC LONG-PASS OPTICAL FILTER BLAZE BIOSCIENCE INC (US) 2026-01-08 — — US claimed
WO-2024011209-A2 ENGINEERED LIQUID CRYSTAL SHUTTER AS A DYNAMIC LONG-PASS OPTICAL FILTER Blaze Bioscience, Inc. (US) 2024-01-11 — — WO claimed
EP-4172600-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2023-05-03 — — EP claimed
CN-116034301-A System and method for simultaneous near infrared and visible imaging 光明之火生物科学公司 2023-04-28 — — CN claimed
US-20220346650-A1 SYSTEMS AND METHODS FOR VASCULAR AND STRUCTURAL IMAGING BLAZE BIOSCIENCE INC (US) 2022-11-03 — — US claimed
EP-4037553-A1 SYSTEMS AND METHODS FOR VASCULAR AND STRUCTURAL IMAGING Blaze Bioscience, Inc. (US) 2022-08-10 — — EP claimed
WO-2021263159-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2021-12-30 — — WO claimed
WO-2021067563-A1 SYSTEMS AND METHODS FOR VASCULAR AND STRUCTURAL IMAGING Blaze Bioscience, Inc. (US) 2021-04-08 — — WO claimed
EP-3773137-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2021-02-17 — — EP claimed
US-20210015350-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2021-01-21 — — US claimed
WO-2019191497-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2019-10-03 — — WO claimed
WO-2017032487-A1 PROTEASOME INHIBITOR COMPRISING A SIGNAL-EMITTING MOIETY Technische Universität München (DE) 2017-03-02 — — WO claimed
CN-104303059-B Method for detecting intracellular infectious agents in sperm cells 瓦西利奥斯·齐列瓦可斯 2016-08-17 — — CN claimed
US-20150204885-A1 METHOD FOR THE DIRECT DETECTION OF MYCOBACTERIUM TUBERCULOSIS TSILIVAKOS, VASSILIOS (GR) 2015-07-23 — — US claimed
EP-2882861-A2 METHOD FOR THE DIRECT DETECTION OF MYCOBACTERIUM TUBERCULOSIS Poulakis, Nicolaos (GR) 2015-06-17 — — EP claimed
US-20150064691-A1 METHOD OF INTRACELLULAR INFECTIOUS AGENT DETECTION IN SPERM CELLS TSILIVAKOS VASSILIOS (GR) 2015-03-05 — — US claimed
EP-2831588-A1 METHOD OF INTRACELLULAR INFECTIOUS AGENT DETECTION IN SPERM CELLS Tsilivakos, Vassilios (GR) 2015-02-04 — — EP claimed
WO-2014023984-A2 METHOD FOR THE DIRECT DETECTION OF MYCOBACTERIUM TUBERCULOSIS POULAKIS NICOLAOS (GR) 2014-02-13 — — WO claimed
WO-2013144662-A1 METHOD OF INTRACELLULAR INFECTIOUS AGENT DETECTION IN SPERM CELLS TSILIVAKOS VASSILIOS (GR) 2013-10-03 — — WO claimed
WO-2009064366-A2 METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-05-22 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260010026-A1 ENGINEERED LIQUID CRYSTAL SHUTTER AS A DYNAMIC LONG-PASS OPTICAL FILTER CRYZ, TRPC3, TRPC1 GAA 4782/4885MGAM 2966/4885SI 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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