Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497488 | 0.89 | KDM4E (0.57) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL1494485 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL3660398 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL1494490 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL10693613 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL23710624 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL29471286 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL6300238 | 0.86 | KDM4E (0.69) | KDM4EPKMLMNATP53ADORA2A | |
| SCHEMBL29997464 | 0.83 | KDM4E (1.00) | KDM4EPKMLMNATP53ADORA2A | |
| Xanthosine SCHEMBL11523732 | 0.82 | LMNA (0.65) | LMNATP53ADORA2AADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080466-A1 | CYTIDINE ANALOGS AND METHODS OF USE | RIBAPHARM INC. (US) | 2004-09-23 | — | — | WO | disclosed |