SCHEMBL1494485

SCHEMBL1494485

Nc1ncc2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.69
▸ PKM P14618 1/20 0.69
▸ LMNA P02545 2/20 0.64
▸ GMNN O75496 1/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ TP53 P04637 1/20 0.64
▸ NFKB1 P19838 1/20 0.64
▸ DNMT1 P26358 1/20 0.64
▸ THPO P40225 1/20 0.64
▸ MTOR P42345 1/20 0.64
▸ HTT P42858 1/20 0.64
▸ RAB9A P51151 1/20 0.64
▸ BLM P54132 1/20 0.64
▸ HBB P68871 1/20 0.64
▸ PMP22 Q01453 1/20 0.64
▸ CYP2C19 P33261 1/20 0.61
▸ ADORA3 P0DMS8 2/20 0.60
▸ ADORA1 P30542 2/20 0.60
▸ SLC29A1 Q99808 2/20 0.60
▸ PGK1 P00558 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471286 1.00 KDM4E (0.69) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL1494490 1.00 KDM4E (0.69) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL23710624 1.00 KDM4E (0.69) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL8970975 0.89 ADORA3 (0.60) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL8970966 0.89 ADORA3 (0.60) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL9150473 0.89 KDM4E (0.56) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL25342616 0.86 KDM4E (0.56) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL6687832 0.86 KDM4E (0.71) KDM4EPKMLMNAGMNNALDH1A1
SCHEMBL6300238 0.85 KDM4E (0.69) KDM4EPKMLMNATP53ADORA3
SCHEMBL3660398 0.85 KDM4E (0.69) KDM4EPKMLMNAGMNNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 — — EP claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 — — WO claimed
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CUREVAC AG (DE) 2022-01-06 — — US claimed
EP-3350343-B1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING PETAOMICS INC (US) 2020-04-22 — — EP claimed
CN-104804903-B Semiconductor cleaning agent with metal line 恩特格里斯公司 2018-10-30 — — CN claimed
EP-3350343-A1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING Petaomics, Inc. (US) 2018-07-25 — — EP claimed
WO-2017049213-A1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING PetaOmics, Inc. (US) 2017-03-23 — — WO claimed
US-9476019-B2 Cleaning agent for semiconductor provided with metal wiring ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2016-10-25 — — US claimed
US-20160032221-A1 COPPER CLEANING AND PROTECTION FORMULATIONS ENTEGRIS, INC. 2016-02-04 — — US claimed
US-20150259632-A1 CLEANING AGENT FOR SEMICONDUCTOR PROVIDED WITH METAL WIRING TRUIST BANK, AS NOTES COLLATERAL AGENT 2015-09-17 — — US claimed
US-9045717-B2 Cleaning agent for semiconductor provided with metal wiring ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2015-06-02 — — US claimed
CN-102770524-B cleaning agent for semiconductor with metal wiring ADVANCED TECH MATERIALS 2015-04-22 — — CN claimed
CN-102197124-B Copper cleaning and protection formulations ADVANCED TECH MATERIALS 2013-12-18 — — CN claimed
WO-2013138278-A1 COPPER CLEANING AND PROTECTION FORMULATIONS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2013-09-19 — — WO claimed
US-20130203643-A1 CLEANING AGENT FOR SEMICONDUCTOR PROVIDED WITH METAL WIRING ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2013-08-08 — — US claimed
US-20120283163-A1 COPPER CLEANING AND PROTECTION FORMULATIONS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2012-11-08 — — US claimed
CN-102770524-A Cleaning agent for semiconductor with metal wiring ADVANCED TECH MATERIALS 2012-11-07 — — CN claimed
CN-102197124-A Copper cleaning and protection formulations ADVANCED TECH MATERIALS 2011-09-21 — — CN claimed
WO-2010048139-A2 COPPER CLEANING AND PROTECTION FORMULATIONS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2010-04-29 — — WO claimed
CN-1466591-A Nucleoside derivatives - 2004-01-07 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CPSF6, CPSF1, RNMT KDM4E 3150/4885PKM 1054/4885LMNA 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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