Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.66 |
| ▸ | CNR1 | P21554 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236638 | 0.90 | EPHX1 (0.62) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31300137 | 0.84 | ROCK2 (0.66) | CASRCNR1HTTROCK2ROCK1 | |
| SCHEMBL6689395 | 0.83 | RNF4 (0.68) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8573559 | 0.81 | CNR1 (0.61) | CASRCNR1RAB9AALDH1A1HTT | |
| SCHEMBL10939812 | 0.81 | CNR1 (0.70) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6690096 | 0.81 | MAOA (0.53) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14424453 | 0.81 | EPHX1 (0.72) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14424478 | 0.80 | EPHX1 (0.80) | CASRCNR1ALDH1A1HTTHTR3A | |
| SCHEMBL2433648 | 0.80 | CASR (1.00) | CASRCNR1ROCK2ROCK1 | |
| SCHEMBL4708584 | 0.79 | CNR1 (0.50) | CASRCNR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |