Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687988 | 1.00 | MRGPRX4 (0.50) | MRGPRX4CD274MTNR1AMTNR1BFFAR1 | |
| SCHEMBL6690014 | 0.90 | MTNR1A (0.54) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL6690026 | 0.90 | MTNR1A (0.54) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL6690337 | 0.87 | MAOB (0.54) | — | |
| SCHEMBL6690341 | 0.87 | MAOB (0.54) | — | |
| SCHEMBL6693520 | 0.85 | MTNR1A (0.55) | MRGPRX4MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL6693523 | 0.85 | MTNR1A (0.55) | MRGPRX4MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL6687960 | 0.82 | MAOB (0.56) | — | |
| SCHEMBL6687957 | 0.82 | MAOB (0.56) | — | |
| SCHEMBL6690108 | 0.77 | SMN1; SMN2 (0.56) | MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |