Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684519 | 0.91 | HRH3 (0.33) | HRH3KCNH2MEN1KMT2AACHE | |
| SCHEMBL6689578 | 0.84 | TSHR (0.43) | HRH3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL18024010 | 0.81 | HRH3 (0.53) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL18024040 | 0.81 | HRH3 (0.50) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL6691974 | 0.79 | POLB (0.46) | HRH3CHRM2KCNH2SIGMAR1CYP1A2 | |
| SCHEMBL18024044 | 0.78 | HRH3 (0.46) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL18024004 | 0.78 | HRH3 (0.50) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL6688087 | 0.78 | HRH3 (0.36) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL3303147 | 0.78 | TSHR (0.47) | HRH3HRH1SLC6A2ADRA2CCHRM2 | |
| SCHEMBL3307520 | 0.77 | LTA4H (0.46) | HRH3HRH1SLC6A2ADRA2CCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |