Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687504 | 0.94 | HRH3 (0.36) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL6684514 | 0.91 | HRH3 (0.33) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL6689574 | 0.84 | LMNA (0.31) | HRH3MAPT | |
| SCHEMBL6691972 | 0.79 | KEAP1 (0.36) | HRH3HRH1KCNH2CHRM2SIGMAR1 | |
| SCHEMBL6688091 | 0.78 | HRH3 (0.37) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL3303147 | 0.78 | TSHR (0.47) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL3307520 | 0.77 | LTA4H (0.46) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL6684238 | 0.77 | HRH3 (0.36) | HRH3ADRA2CCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL2494566 | 0.76 | TSHR (0.44) | HRH3HRH1SLC6A2ADRA2CKCNH2 | |
| SCHEMBL346747 | 0.75 | HRH3 (0.43) | HRH3ADRA2CCHRM5MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |