Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094679 | 0.78 | BRD4 (0.40) | MAPTNPSR1 | |
| SCHEMBL6688230 | 0.76 | LMNA (0.35) | TMEM97SIGMAR1POLBRAB9AALDH1A1 | |
| SCHEMBL6688243 | 0.76 | LMNA (0.35) | TMEM97SIGMAR1POLBRAB9AALDH1A1 | |
| SCHEMBL4307213 | 0.75 | GAA (0.43) | RAB9AALDH1A1NPC1LMNASMN1; SMN2 | |
| SCHEMBL6096675 | 0.69 | BRD4 (0.41) | MAPTNPSR1 | |
| SCHEMBL4199059 | 0.68 | EGFR (0.54) | POLBMAPTTP53 | |
| SCHEMBL4199068 | 0.68 | EGFR (0.54) | POLBMAPTTP53 | |
| SCHEMBL5793540 | 0.67 | KMT2A (0.40) | RAB9AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5793537 | 0.67 | KMT2A (0.40) | RAB9AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL20324343 | 0.66 | MAPT (0.43) | POLBRAB9AALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451186-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050119-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |