Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688230 | 1.00 | LMNA (0.35) | LMNASMN1; SMN2NPSR1TMEM97SIGMAR1 | |
| SCHEMBL6094679 | 0.85 | BRD4 (0.40) | NPSR1DRD2MAPTKMT2AMEN1 | |
| SCHEMBL6688237 | 0.76 | TMEM97 (0.34) | LMNASMN1; SMN2NPSR1TMEM97SIGMAR1 | |
| SCHEMBL4307213 | 0.76 | GAA (0.43) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6096675 | 0.76 | BRD4 (0.41) | NPSR1MAPTKMT2AMEN1 | |
| SCHEMBL14340741 | 0.72 | LMNA (0.41) | LMNASMN1; SMN2MAPTALDH1A1NR3C1 | |
| SCHEMBL4793194 | 0.70 | BCHE (0.36) | ALDH1A1KMT2APOLB | |
| SCHEMBL5793537 | 0.69 | KMT2A (0.40) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL5793540 | 0.69 | KMT2A (0.40) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL4792946 | 0.68 | GAA (0.38) | LMNASMN1; SMN2NPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451186-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050119-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |