Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235877 | 0.82 | CYP2A6 (0.47) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL3565505 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTCA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL7794806 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL27644720 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL12915440 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL14335680 | 0.75 | TSHR (0.52) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL22781056 | 0.74 | SIGMAR1 (0.37) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL11756264 | 0.72 | LMNA (0.48) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL16233138 | 0.72 | MAPT (0.41) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL3572170 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451442-A2 | Process for preparing methylene-crosslinked polyraylamine. | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-16 | — | — | EP | claimed |
| JP-3294249-A | — | — | None | — | — | JP | disclosed |
| EP-2421818-B1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8614352-B2 | Method for producing color-stable MDA and MDI | BASF SE (DE) | 2013-12-24 | — | — | US | disclosed |
| EP-2421818-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20120046497-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2012-02-23 | — | — | US | disclosed |
| WO-2010121997-A1 | METHOD FOR PRODUCING COLOR-STABLE MDA AND MDI | BASF SE (DE) | 2010-10-28 | — | — | WO | disclosed |
| EP-0752414-B1 | Process for the production of aromatic urethanes | MINI RICERCA SCIENT TECNOLOG (IT) | 1999-05-06 | — | — | EP | disclosed |
| CN-1034119-C | Methylene-crosslinked polyarylamine and process for preparing same | MITSUI TOATSU CHEMICALS (JP) | 1997-02-26 | — | — | CN | disclosed |
| EP-0752414-A1 | Process for the production of aromatic urethanes | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | disclosed |
| EP-0451442-B1 | Process for preparing methylene-crosslinked polyraylamine. | MITSUI TOATSU CHEMICALS (JP) | 1994-09-21 | — | — | EP | disclosed |
| JP-H03294249-A | PRODUCTION OF POLYARYLAMINE CROSSLINKED WITH METHYLENE | MITSUI TOATSU CHEM INC | 1991-12-25 | — | — | JP | disclosed |
| EP-0451442-A2 | Process for preparing methylene-crosslinked polyraylamine. | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0451442-A2 | Process for preparing methylene-crosslinked polyraylamine. | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-5053539-A | METHYLENE-CROSSLINKED POLYARYLAMINE AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-10-01 | — | — | US | disclosed |
| US-5053539-A | METHYLENE-CROSSLINKED POLYARYLAMINE AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0248628-A2 | Polyurea-Polyurethane from the reaction of a polyol, an aromatic amine and an isocyanate terminated polyoxy-propylene prepolymer | ICI AMERICAS INC. (US) | 1987-12-09 | — | — | EP | disclosed |