Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409137 | 0.92 | KMT2A (0.38) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL1409136 | 0.92 | KMT2A (0.38) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL7475394 | 0.85 | PTPN1 (0.44) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL4192820 | 0.82 | PTPN1 (0.61) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL6688709 | 0.76 | BACE1 (0.60) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL1409019 | 0.75 | PTPN1 (0.54) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL4891285 | 0.72 | MEN1 (0.50) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL7474177 | 0.72 | PTPN1 (0.42) | ALDH1A1RAB9AMAPTNPC1KDM4E | |
| SCHEMBL4176541 | 0.69 | PTPN1 (0.55) | ALDH1A1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL6850488 | 0.66 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | claimed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | claimed |
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | disclosed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |
| EP-1025107-A1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020630-A1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |