SCHEMBL668874

SCHEMBL668874

O=c1[nH]c(=O)n([C@H]2O[C@@H](COP(=O)(O)O)C(O)C2O)cc1F

nearest known ligand 0.80

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 7/20 0.80
P2RY14 Q15391 4/20 0.80
NT5E P21589 1/20 0.80
DNPH1 O43598 1/20 0.74
UMPS P11172 3/20 0.62
P2RY2 P41231 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686864 1.00 P2RY6 (0.80) P2RY6P2RY14NT5EDNPH1UMPS
SCHEMBL465109 1.00 P2RY6 (0.80) P2RY6P2RY14NT5EDNPH1UMPS
Lithium Ion SCHEMBL29357540 0.99 P2RY6 (0.79) P2RY6P2RY14NT5EDNPH1UMPS
SCHEMBL9702618 0.91 P2RY6 (0.74) P2RY6P2RY14NT5EDNPH1P2RY2
SCHEMBL9702628 0.91 P2RY6 (0.74) P2RY6P2RY14NT5EDNPH1P2RY2
SCHEMBL28741430 0.91 P2RY6 (0.74) P2RY6P2RY14NT5EDNPH1P2RY2
SCHEMBL9551479 0.91 P2RY6 (0.77) P2RY6P2RY14NT5EDNPH1TSHR
SCHEMBL10932987 0.91 P2RY6 (0.77) P2RY6P2RY14NT5EDNPH1TSHR
SCHEMBL148676 0.90 P2RY6 (0.73) P2RY6P2RY14NT5EDNPH1P2RY2
SCHEMBL148675 0.90 P2RY6 (0.73) P2RY6P2RY14NT5EDNPH1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021260322-A1 STRAINS OF CLOSTRIDIUM BACTERIA RESISTANT TO 5-FLUOROURACIL, GENETIC TOOLS AND USES THEREOF IFP Energies Nouvelles (FR) 2021-12-30 WO claimed
EP-0791056-B1 LIPID-CLEAVAGE ENZYME COMPLEX HEIDELBERG PHARMA GMBH (DE) 2005-03-30 EP claimed
US-20030082167-A1 Lapid cleavage enzyme HEIDELBERG PHARMA HOLDING GMBH 2003-05-01 US claimed
US-20020106363-A1 LIPID CLEAVAGE ENZYME HEIDELBERG PHARMA HOLDING GMBH (DE) 2002-08-08 US claimed
EP-0302473-B1 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells BRISTOL MYERS SQUIBB CO (US) 1995-02-15 EP claimed
US-4975278-A Converting the prodrug at the tumor site to the active drug by means of the conjugate bound to a tumor surface antigen BRISTOL-MYERS COMPANY (US) 1990-12-04 US claimed
EP-0302473-A2 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells Bristol-Myers Squibb Company (US) 1989-02-08 EP claimed
JP-53029937-A None JP disclosed
JP-53031677-A None JP disclosed
EP-4696780-A1 METHOD FOR TRANSFORMING BACTERIUM BELONGING TO GENUS BIFIDOBACTERIUM Kabushiki Kaisha Yakult Honsha (JP) 2026-02-18 EP disclosed
EP-4689059-A1 MODIFIED CLOSTRIDIUM BACTERIA, GENETIC EDITING TOOL FOR THE PSOL PLASMID OF CLOSTRIDIUM BACTERIA AND USES THEREOF IFP Energies nouvelles (FR) 2026-02-11 EP disclosed
EP-4689128-A1 NUCLEIC ACID MOLECULE AND METHODS Forge Genetics Ltd (GB) 2026-02-11 EP disclosed
WO-2024209201-A1 NUCLEIC ACID MOLECULE AND METHODS THE UNIVERSITY OF NOTTINGHAM (GB) 2024-10-10 WO disclosed
US-5552440-A Use of L-canavanine as a chemotherapeutic agent for the treatment of pancreatic cancer THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1996-09-03 US disclosed
EP-0302473-B1 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells BRISTOL MYERS SQUIBB CO (US) 1995-02-15 EP disclosed
EP-0540859-A1 Anthracycline prodrugs Bristol-Myers Squibb Company (US) 1993-05-12 EP disclosed
US-4975278-A Converting the prodrug at the tumor site to the active drug by means of the conjugate bound to a tumor surface antigen BRISTOL-MYERS COMPANY (US) 1990-12-04 US disclosed
EP-0302473-A2 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells Bristol-Myers Squibb Company (US) 1989-02-08 EP disclosed
JP-S5331677-A 5-FLUOROURIDYLIC ACID DERIVATIVES AND THEIR PREPARATION MITSUI TOATSU CHEM INC 1978-03-25 JP disclosed
JP-S5329937-A CARCINOSTATIC AGENT MITSUI TOATSU CHEM INC 1978-03-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082167-A1 Lapid cleavage enzyme LAP3, NAALAD2, ENGASE P2RY6 3635/4885P2RY14 2861/4885NT5E 621/4885
US-20020106363-A1 LIPID CLEAVAGE ENZYME SMPD1, MMEL1, ENGASE P2RY6 3422/4885P2RY14 2684/4885NT5E 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.