SCHEMBL148676

SCHEMBL148676

O=c1[nH]c(=O)n([C@H]2O[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)cc1F

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 14/20 0.73
P2RY2 P41231 10/20 0.73
P2RY14 Q15391 2/20 0.72
NT5E P21589 1/20 0.72
P2RY4 P51582 5/20 0.64
DNPH1 O43598 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148675 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL9702628 0.98 P2RY6 (0.74) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL9702618 0.98 P2RY6 (0.74) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL8861497 0.94 P2RY6 (0.75) P2RY6P2RY2P2RY14NT5E
SCHEMBL6820202 0.92 P2RY6 (0.63) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL16081117 0.92 P2RY2 (0.72) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL6820199 0.92 P2RY6 (0.63) P2RY6P2RY2P2RY14NT5EP2RY4
SCHEMBL28741430 0.90 P2RY6 (0.74) P2RY6P2RY2P2RY14NT5EDNPH1
SCHEMBL465109 0.90 P2RY6 (0.80) P2RY6P2RY2P2RY14NT5EDNPH1
SCHEMBL27686864 0.90 P2RY6 (0.80) P2RY6P2RY2P2RY14NT5EDNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210275562-A1 CANCER TREATMENT METHODS STACEY DENNIS W (US) 2021-09-09 US claimed
EP-2935331-B1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF ABBVIE INC (US) 2018-02-28 EP claimed
EP-2935331-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF AbbVie Inc. (US) 2015-10-28 EP claimed
US-20140227294-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF ABBVIE INC. (US) 2014-08-14 US claimed
WO-2014105810-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF ABBVIE INC. (US) 2014-07-03 WO claimed
US-12551570-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2026-02-17 US disclosed
US-12479927-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2025-11-25 US disclosed
US-12419893-B2 Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine TOSK, INC. (US) 2025-09-23 US disclosed
US-20250186435-A1 PHARMACEUTICAL FORMULATIONS AND THEIR PREPARATIONS FOR TREATMENT OF CANCER CELLIX BIO PRIVATE LIMITED (IN) 2025-06-12 US disclosed
US-20250163159-A1 ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-05-22 US disclosed
US-20250121087-A1 ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES INTOCELL, INC. (KR) 2025-04-17 US disclosed
US-12168060-B2 Antibody-drug conjugates comprising anti-B7-H3 antibodies INTOCELL, INC. (KR) 2024-12-17 US disclosed
US-5654286-A Nucleotides for topical treatment of psoriasis, and methods for using same HOSTETLER KARL Y (US) 1997-08-05 US disclosed
US-5620676-A ADENOSINE TRIPHOSPHATE DERIVATIVES; TREATMENT OF SEPTIC SHOCK OR BRAIN SEIZURES, LEARNING ENHANCEMENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-04-15 US disclosed
WO-1996040165-A1 METHODS OF REDUCING TOXICITY OF CHEMOTHERAPEUTIC AND ANTIVIRAL AGENTS WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO-NEURON, INC. (US) 1996-12-19 WO disclosed
WO-1996040166-A1 NUCLEOTIDE ANALOGUES FOR TOPICAL TREATMENT OF PROLIFERATIVE DISEASE OF THE SKIN HOSTETLER KARL Y (US) 1996-12-19 WO disclosed
WO-1994026761-A1 TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO-NEURON, INC. (US) 1994-11-24 WO disclosed
EP-0591462-A1 UNIVERSAL DONOR CELLS Oklahoma Medical Research Foundation (US) 1994-04-13 EP disclosed
WO-1994000560-A1 MATRIX FOR UNIVERSAL DONOR MICROVASCULAR ENDOTHELIAL CELLS ALEXION PHARMACEUTICALS, INC. (US) 1994-01-06 WO disclosed
WO-1993002188-A1 UNIVERSAL DONOR CELLS OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1993-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227294-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF PRLHR, LHCGR, FCGR2A P2RY6 2607/4885P2RY2 2361/4885P2RY14 2273/4885
US-20250121087-A1 ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES CD274, CD44, H1-3 P2RY6 3161/4885P2RY2 3679/4885P2RY14 3560/4885
US-12419893-B2 Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine UMPS, UNG, UGDH P2RY6 686/4885P2RY2 872/4885P2RY14 1778/4885
US-12551570-B2 Compounds comprising cleavable linker and uses thereof FCGR2A, FCGR3B, FCGR1A P2RY6 3005/4885P2RY2 2547/4885P2RY14 3131/4885
US-12168060-B2 Antibody-drug conjugates comprising anti-B7-H3 antibodies CD274, CD44, H1-3 P2RY6 3161/4885P2RY2 3679/4885P2RY14 3560/4885
US-12479927-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 P2RY6 823/4885P2RY2 1008/4885P2RY14 547/4885
US-20250163159-A1 ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 P2RY6 3359/4885P2RY2 3988/4885P2RY14 3786/4885
US-20250186435-A1 PHARMACEUTICAL FORMULATIONS AND THEIR PREPARATIONS FOR TREATMENT OF CANCER SLC5A1, DPYD, SLC46A1 P2RY6 281/4885P2RY2 1359/4885P2RY14 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.