SCHEMBL6689004

SCHEMBL6689004

CSc1[c]ccc(C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40745 0.76 MCL1 (0.31)
SCHEMBL15654795 0.74
SCHEMBL18860926 0.74
SCHEMBL28002860 0.73 HTR1A (0.35)
SCHEMBL1636355 0.71 CA1 (0.35)
SCHEMBL1638285 0.71 TRPA1 (0.34)
SCHEMBL11409784 0.70 HDAC8 (0.34)
SCHEMBL7769605 0.70 RECQL (0.31)
SCHEMBL7049757 0.69 ACHE (0.38)
SCHEMBL2973 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1692115-A Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group TAISHO PHARMACEUTICAL CO LTD (JP) 2005-11-02 CN disclosed
EP-0987567-B1 A sulfur-containing (thio)ether (co)polymer and a use thereof MITSUI CHEMICALS INC (JP) 2004-04-07 EP disclosed
US-6320020-B1 POLYMER OR COPOLYMER CONTAINING A SULFUR ATOM WHOSE PRINCIPAL BACKBONE COMPRISES ETHER AND/OR THIOETHER BONDS; OPTICAL DISK SUBSTRATE; A LIQUID-CRYSTAL PLASTIC SUBSTRATE; VARIOUS OPTICAL LENSES INCLUDING AN EYEGLASS; AND AN LED SEALING COAT. MITSUI CHEMICALS, INC. (JP) 2001-11-20 US disclosed
EP-0987567-A1 A sulfur-containing (thio)ether (co)polymer and a use thereof Mitsui Chemicals, Inc. (JP) 2000-03-22 EP disclosed
US-4292232-A Process for the mass coloration of thermoplastics with anthraquinonylaminotraizines CIBA-GEIGY CORPORATION (US) 1981-09-29 US disclosed
US-4151279-A Fungicidal N-carbamyloxy-2,3-disubstituted 4-trihalomethyl-6-oxotetrahydro-1,3-oxazines CHEVRON RESEARCH COMPANY (US) 1979-04-24 US disclosed