SCHEMBL6689098

SCHEMBL6689098

Cc1cn([C@H]2CC[C@@H](COP(=O)(O)C(F)(F)P(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.53
P2RY14 Q15391 2/20 0.51
P2RY6 Q15077 1/20 0.51
POLB P06746 2/20 0.49
POLA1 P09884 1/20 0.49
POLD1 P28340 1/20 0.49
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14378706 0.91 TK1 (0.49) TK1P2RY14P2RY6POLBPOLA1
SCHEMBL14378752 0.91 TK1 (0.49) TK1P2RY14P2RY6POLBPOLA1
SCHEMBL14378754 0.89 TK1 (0.47) TK1P2RY14P2RY6POLBPOLA1
SCHEMBL14378755 0.89 TK1 (0.47) TK1P2RY14P2RY6POLBPOLA1
SCHEMBL6420653 0.86 TK1 (0.58) TK1POLBPOLA1POLD1BCHE
SCHEMBL23440065 0.86 TK1 (0.67) TK1POLBPOLA1POLD1
SCHEMBL8883 0.86 TK1 (0.67) TK1POLBPOLA1POLD1
SCHEMBL28774920 0.86 TK1 (0.67) TK1POLBPOLA1POLD1
SCHEMBL26757571 0.86 TK1 (0.67) TK1POLBPOLA1POLD1
SCHEMBL13245040 0.85 TK1 (0.57) TK1POLBPOLA1POLD1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 WO disclosed