SCHEMBL6690610

SCHEMBL6690610

CCOc1ccc2sc(SSc3nc4cc(OCC)ccc4s3)nc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 2/20 0.53
MAPT P10636 8/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
LMNA P02545 3/20 0.52
MAPK1 P28482 1/20 0.52
PPARA Q07869 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
HTT P42858 2/20 0.51
ALDH1A1 P00352 6/20 0.50
KMT2A Q03164 5/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
MEN1 O00255 4/20 0.47
POLB P06746 1/20 0.47
CTSD P07339 1/20 0.47
HPGD P15428 5/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900275 0.91 MAPT (0.52) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL6690979 0.88 PDK1 (0.50) PDK1MAPTL3MBTL1LMNAMAPK1
SCHEMBL8635959 0.88 MAPT (0.50) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL8654041 0.88 ALDH1A1 (0.51) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL6689290 0.88 PDK1 (0.69) PDK1MAPTL3MBTL1LMNAMAPK1
SCHEMBL22190296 0.84 PPARA (0.55) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL6697921 0.84 MAPT (0.49) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL24086130 0.82 MAPT (0.46) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL6691229 0.82 PPARA (0.50) MAPTL3MBTL1LMNAMAPK1PPARA
SCHEMBL6690265 0.82 PDK1 (0.76) PDK1MAPTLMNAMAPK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
EP-0890605-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2003-04-23 EP disclosed
EP-1277795-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-22 EP disclosed
US-20020010283-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-01-24 US disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
US-6186204-B1 EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-02-13 US disclosed
EP-0890605-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 1999-01-13 EP disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed
EP-0854168-A1 Rubber composition Bridgestone Corporation (JP) 1998-07-22 EP disclosed
US-4343660-A PETROLEUM SULFONATE AND COMPLEXING AGENT, FOR COPPER CABLES PETROLITE CORPORATION (US) 1982-08-10 US disclosed
US-4138346-A ETHOXYLATED PHOSPHATE ESTER WITH A MERCAPTOTHIAZOLE, A DITHIOBIS-THIAZOLE, A SULFIDE, A DISULFIDE OR A SULFONE BASF WYANDOTTE CORPORATION (US) 1979-02-06 US disclosed