Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686746 | 0.86 | MAPT (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5098238 | 0.81 | MEN1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL6233072 | 0.80 | RECQL (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5097715 | 0.77 | KMT2A (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5097658 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL6687431 | 0.75 | TP53 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL7073510 | 0.74 | TP53 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8819461 | 0.70 | SMN1; SMN2 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL393138 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6686449 | 0.68 | MAPT (0.35) | MEN1KMT2AHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |