Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689528 | 0.86 | MEN1 (0.39) | MAPTNPC1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5097715 | 0.80 | KMT2A (0.42) | MAPTL3MBTL1NPC1ALDH1A1CYP3A4 | |
| SCHEMBL6233072 | 0.78 | RECQL (0.40) | MAPTNPC1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5098238 | 0.77 | MEN1 (0.41) | NPC1ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6686449 | 0.76 | MAPT (0.35) | MAPTALDH1A1TSHRGAALMNA | |
| SCHEMBL6686427 | 0.75 | LMNA (0.40) | MAPTHTR1AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5097658 | 0.75 | ALDH1A1 (0.54) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6687431 | 0.73 | TP53 (0.39) | MAPTL3MBTL1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7073510 | 0.72 | TP53 (0.39) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8819461 | 0.68 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2LMNADPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |