Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687177 | 0.86 | GAA (0.35) | MAPTALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6686427 | 0.80 | LMNA (0.40) | MAPTALDH1A1RAB9AHPGDHSD17B10 | |
| SCHEMBL6686746 | 0.76 | MAPT (0.41) | MAPTALDH1A1RAB9AGAATSHR | |
| SCHEMBL6689528 | 0.68 | MEN1 (0.39) | MAPTALDH1A1RAB9AHPGDHSD17B10 | |
| SCHEMBL27649383 | 0.68 | CHEK1 (0.37) | ALDH1A1RAB9AHPGDHSD17B10MEN1 | |
| SCHEMBL5097715 | 0.68 | KMT2A (0.42) | MAPTALDH1A1RAB9ATSHRMEN1 | |
| SCHEMBL5097658 | 0.68 | ALDH1A1 (0.54) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6233072 | 0.66 | RECQL (0.40) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL335430 | 0.66 | MEN1 (0.34) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL27649419 | 0.65 | LMNA (0.33) | MAPTALDH1A1RAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |