Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071797 | 0.92 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL20135982 | 0.90 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL12831232 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL3136850 | 0.85 | ALDH1A1 (0.90) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL16145897 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7724901 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL27187284 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL18901650 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL12831233 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1TAAR1 | |
| SCHEMBL20022271 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606176-B1 | THERMAL TREATMENT | UNIV ASTON (GB) | 2014-10-08 | — | — | EP | disclosed |
| EP-2606176-A1 | THERMAL TREATMENT | Aston University (GB) | 2013-06-26 | — | — | EP | disclosed |
| US-20130118886-A1 | Thermal Treatment | ASTON UNIVERSITY (GB) | 2013-05-16 | — | — | US | disclosed |
| WO-2012022949-A1 | THERMAL TREATMENT | ASTON UNIVERSITY (GB) | 2012-02-23 | — | — | WO | disclosed |
| US-4000197-A | FROM PHENYLACETONES AND METHYL BENZYLAMINE, REDUCTION, HYDROGENOLYSIS | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1976-12-28 | — | — | US | disclosed |