Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761533 | 0.92 | ALDH1A1 (0.74) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL10969853 | 0.92 | LMNA (0.68) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL15515870 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL23783245 | 0.88 | LMNA (0.70) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL15517018 | 0.88 | LMNA (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL3431542 | 0.88 | LMNA (0.69) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL3136850 | 0.85 | ALDH1A1 (0.90) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL668963 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL29955060 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL27620235 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173435-A1 | SEMICONDUCTING MIXTURES | Merck Patent GmbH (DE) | 2017-05-31 | — | — | EP | disclosed |