Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490476 | 0.93 | MEN1 (0.42) | MAPTKMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL6490132 | 0.82 | LCK (0.39) | MAPTSMN1; SMN2NPC1HTR1ADRD2 | |
| SCHEMBL6492454 | 0.82 | MAPT (0.41) | MAPTKMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL6501876 | 0.80 | CA1 (0.42) | HTR1ADRD2KDM4EALDH1A1SLC6A4 | |
| SCHEMBL6498772 | 0.78 | MAPT (0.58) | MAPTKMT2ASMN1; SMN2HTTRAB9A | |
| SCHEMBL6502650 | 0.77 | MAPT (0.47) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6503264 | 0.76 | HTR1A (0.51) | MAPTSMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL6499900 | 0.75 | DRD2 (0.46) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6487913 | 0.75 | CHRNB2 (0.43) | KMT2ANPC1RAB9ATP53 | |
| SCHEMBL6499989 | 0.74 | NPC1 (0.53) | MAPTKMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |