Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691516 | 0.93 | MAPK1 (0.53) | MAPK1L3MBTL1NPC1RAB9AATM | |
| SCHEMBL6686093 | 0.92 | MAPK1 (0.52) | MAPK1L3MBTL1NPC1RAB9AATM | |
| SCHEMBL6679218 | 0.90 | MAPK1 (0.64) | MAPK1L3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL6684355 | 0.89 | CYP1A1 (0.50) | MAPK1L3MBTL1NPC1RAB9AATM | |
| SCHEMBL6688390 | 0.89 | L3MBTL1 (0.62) | MAPK1L3MBTL1NPC1RAB9AATM | |
| SCHEMBL6680293 | 0.89 | L3MBTL1 (0.71) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6687181 | 0.86 | NPC1 (0.63) | MAPK1NPC1RAB9AATMALDH1A1 | |
| SCHEMBL6691306 | 0.85 | AURKA (0.66) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6687800 | 0.85 | LMNA (0.59) | L3MBTL1RAB9AATMALDH1A1MEN1 | |
| SCHEMBL6689594 | 0.84 | L3MBTL1 (0.64) | L3MBTL1ATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |