Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 7/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | CDK2 | P24941 | 2/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CDK4 | P11802 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680293 | 0.96 | L3MBTL1 (0.71) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6689594 | 0.91 | L3MBTL1 (0.64) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6688390 | 0.90 | L3MBTL1 (0.62) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6685302 | 0.86 | L3MBTL1 (0.57) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6691516 | 0.85 | MAPK1 (0.53) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6687800 | 0.85 | LMNA (0.59) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6689634 | 0.85 | MAPK1 (0.63) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL23392572 | 0.83 | PTGS1 (0.76) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6691310 | 0.83 | PTGS1 (0.76) | AURKAL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6689714 | 0.82 | ALDH1A1 (0.54) | AURKAL3MBTL1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |