SCHEMBL6689694

SCHEMBL6689694

CCCCCCCCCCCCCCCc1cccc(OCC)c1C1C(C(=O)OCCOC)=C(C)NC(C)=C1C(=O)OCCOC

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
LMNA P02545 2/20 0.49
CACNA1F O60840 5/20 0.48
CACNA1D Q01668 5/20 0.48
CACNA1S Q13698 5/20 0.48
CACNA1C Q13936 5/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MTOR P42345 1/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489360 0.99 ALDH1A1 (0.50) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL489551 0.94 ALDH1A1 (0.51) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL489865 0.94 MTOR (0.50) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL489753 0.91 ADORA3 (0.47) ALDH1A1LMNAKDM4EMAPTMTOR
SCHEMBL489543 0.89 PPARA (0.51) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL489303 0.87 CACNA1C (0.47) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL5408190 0.87 PPARA (0.49) ALDH1A1KDM4EMAPTSMN1; SMN2PPARA
SCHEMBL17998996 0.86 PPARA (0.50) LMNACACNA1FCACNA1DCACNA1SCACNA1C
SCHEMBL489737 0.86 CACNA1C (0.43) ALDH1A1LMNACACNA1FCACNA1DCACNA1S
SCHEMBL489368 0.85 LMNA (0.43) ALDH1A1LMNACACNA1FCACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470108-A1 1,4-DIHYDROPYRIDINE AND PYRIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) 2004-10-27 EP disclosed
WO-2003062201-A1 1,4-DIHYDROPYRIDINE AND PYRIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) 2003-07-31 WO disclosed