Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.40 |
| ▸ | UGCG | Q16739 | 9/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689707 | 0.88 | GHSR (0.53) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL6693779 | 0.88 | GHSR (0.53) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL6695783 | 0.88 | GHSR (0.53) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL6691999 | 0.83 | GHSR (0.42) | GHSRUGCGCCKBRCYP3A4TACR1 | |
| SCHEMBL6689699 | 0.82 | GHSR (0.34) | GHSRUGCGCCKBRTACR1 | |
| SCHEMBL6691541 | 0.76 | GHSR (0.54) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL6691543 | 0.76 | GHSR (0.54) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL5227924 | 0.74 | GHSR (0.57) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL5232861 | 0.74 | GHSR (0.57) | GHSRUGCGCCKBRCYP3A4 | |
| SCHEMBL5228854 | 0.74 | GHSR (0.57) | GHSRUGCGCCKBRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002802-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER PROD INC (US) | 2004-12-08 | — | — | EP | claimed |