Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564163 | 0.94 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDCA12SIGMAR1 | |
| SCHEMBL8576604 | 0.93 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDCA12SIGMAR1 | |
| SCHEMBL249846 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TSHRHPGDCA12SIGMAR1 | |
| Nitric Acid SCHEMBL9873962 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TSHRHPGDCA12SIGMAR1 | |
| SCHEMBL9820308 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDCA12SIGMAR1 | |
| SCHEMBL3202573 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL8867793 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL68381 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TSHRHPGDCA12L3MBTL1 | |
| SCHEMBL29699944 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TSHRHPGDCA12L3MBTL1 | |
| SCHEMBL6889642 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDCA12SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357256-C | Method for synthesizing o-aminophenylpropyl alcohol | UNIV SHANGHAI (CN) | 2007-12-26 | — | — | CN | claimed |
| CN-1760173-A | Method for synthesizing o-aminophenylpropyl alcohol | UNIV SHANGHAI (CN) | 2006-04-19 | — | — | CN | claimed |
| EP-3958865-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2025-12-10 | — | — | EP | disclosed |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-02 | — | — | US | disclosed |
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-3700904-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| US-20220378762-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-01 | — | — | US | disclosed |
| US-11339157-B1 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| EP-3958865-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2022-03-02 | — | — | EP | disclosed |
| WO-2020216774-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |
| EP-3700904-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | Bayer AG (DE) | 2020-09-02 | — | — | EP | disclosed |
| US-8658572-B2 | Whole proteome tiling microarrays | ROCHE NIMBLEGEN, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| WO-2013140419-A1 | A PROCESS FOR SYNTHESIS OF CHIRAL 3-SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-09-26 | — | — | WO | disclosed |
| US-20120245057-A1 | WHOLE PROTEOME TILING MICROARRAYS | Roche Sequencing Solutions, Inc. | 2012-09-27 | — | — | US | disclosed |
| US-20120238477-A1 | METHODS FOR SYNTHESIS OF AN OLIGOPEPTIDE MICROARRAY | Roche Sequencing Solutions, Inc. | 2012-09-20 | — | — | US | disclosed |
| CN-100357256-C | Method for synthesizing o-aminophenylpropyl alcohol | UNIV SHANGHAI (CN) | 2007-12-26 | — | — | CN | disclosed |
| CN-1760173-A | Method for synthesizing o-aminophenylpropyl alcohol | UNIV SHANGHAI (CN) | 2006-04-19 | — | — | CN | disclosed |
| WO-2005073389-A1 | METHOD FOR PRODUCING β-HYDROXY NITRO COMPOUNDS MADE FROM ALDEHYDES AND NITROALKANES WHILE USING A HYDROXY NITRILE LYASE | ANGEWANDTE BIOKATALYSE-KOMPETENZZENTRUM GMBH (AT) | 2005-08-11 | — | — | WO | disclosed |
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | MUSK, ERBB2, NTRK1 | ALDH1A1 4113/4885TSHR 652/4885HPGD 3378/4885 |
| US-20220378762-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | EGFR, ERBB2, ERBB4 | ALDH1A1 1255/4885TSHR 2270/4885HPGD 235/4885 |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | EGFR, ERBB2, ERBB4 | ALDH1A1 1255/4885TSHR 2270/4885HPGD 235/4885 |
| US-11339157-B1 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | CYP4B1, CYP2C19, CYP3A4 | ALDH1A1 387/4885TSHR 1659/4885HPGD 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.