Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810707 | 0.75 | MAOA (0.49) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL29377962 | 0.73 | PYCR1 (0.45) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL333032 | 0.73 | PYCR1 (0.45) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL29369408 | 0.72 | PYCR1 (0.40) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL978230 | 0.72 | PYCR1 (0.40) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL5953610 | 0.72 | PYCR1 (0.40) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL5953608 | 0.72 | PYCR1 (0.40) | LMNADRD2DRD4MAOAMAOB | |
| Omigapil SCHEMBL978229 | 0.72 | PYCR1 (0.40) | LMNADRD2DRD4MAOAMAOB | |
| SCHEMBL4043208 | 0.72 | LMNA (0.70) | LMNADRD2DRD4MAOAMAOB | |
| SCHEMBL4038858 | 0.72 | LMNA (0.54) | LMNADRD2DRD4ALOX5GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039773-A2 | COUMPOUNDS MODULATING THE ACTIVITY OF GAPDH AND/OR IAMT | NORDIC BIOSCIENCE A/S (DK) | 2004-05-13 | — | — | WO | disclosed |