Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.80 |
| ▸ | ESR1 | P03372 | 5/20 | 0.80 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289597 | 0.90 | ESR2 (0.82) | ESR2ESR1HSD11B1HSD17B10CYP3A4 | |
| SCHEMBL18187 | 0.89 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| SCHEMBL21291805 | 0.89 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| SCHEMBL4826617 | 0.89 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| SCHEMBL669016 | 0.86 | ESR2 (0.61) | ESR2ESR1HSD11B1HSD17B10CYP3A4 | |
| SCHEMBL822979 | 0.84 | ESR2 (0.88) | ESR2ESR1 | |
| SCHEMBL21624439 | 0.84 | ESR1 (0.88) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| SCHEMBL19751234 | 0.84 | ESR1 (0.88) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| Phenol SCHEMBL7804481 | 0.84 | ESR2 (0.88) | ESR2ESR1CYP3A4CYP2D6TSHR | |
| Phenol SCHEMBL1982817 | 0.84 | ESR2 (0.88) | ESR2ESR1CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130433-A1 | Process for the production of graft polymers | INEOS ABS (JERSEY) LIMITED | 2003-07-10 | — | — | US | disclosed |