Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612453 | 0.72 | ATAD2 (0.44) | ADORA2AADORA2BGAAMAPTKDM4E | |
| SCHEMBL8317662 | 0.68 | RXFP1 (0.45) | RXFP1ALDH1A1PDE3APDE3BPDE2A | |
| SCHEMBL18255880 | 0.67 | MAPK1 (0.46) | ALDH1A1PDE3APDE3BPDE2ACYP3A4 | |
| SCHEMBL10957749 | 0.65 | CSNK2A2 (0.43) | RXFP1ALDH1A1PDE3ACYP3A4PMP22 | |
| SCHEMBL18256005 | 0.64 | PARP1 (0.44) | RXFP1PDE3APDE3BADORA2AADORA3 | |
| SCHEMBL18256035 | 0.64 | RXFP1 (0.45) | RXFP1PDE3APDE3BPDE2AADORA2A | |
| SCHEMBL3289561 | 0.63 | — | — | |
| SCHEMBL3663241 | 0.63 | APAF1 (0.44) | RXFP1ALDH1A1PDE3APDE3BPDE2A | |
| 3-Methylxanthine SCHEMBL237146 | 0.63 | ADORA2A (0.64) | PDE3ACYP3A4PMP22MAPK1ADORA2A | |
| SCHEMBL29361697 | 0.63 | APAF1 (0.44) | RXFP1ALDH1A1PDE3APDE3BPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004514440-A | — | — | 2004-05-20 | — | — | JP | claimed |
| EP-1348035-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | Riken (JP) | 2003-10-01 | — | — | EP | claimed |
| WO-2002044195-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | RIKEN (JP) | 2002-06-06 | — | — | WO | claimed |