Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183489 | 0.85 | RXFP1 (0.49) | RXFP1MPOOPRM1BRD4LMNA | |
| SCHEMBL13238204 | 0.71 | ADORA2B (0.52) | BRD4LMNAALDH1A1TAF1BRPF1 | |
| SCHEMBL613034 | 0.71 | ADORA2A (0.46) | BRD4LMNATAF1BRPF1CREBBP | |
| SCHEMBL12687273 | 0.69 | TYMP (0.51) | BRD4ALDH1A1KDM4EMAPT | |
| SCHEMBL24559423 | 0.68 | OPRM1 (0.38) | RXFP1MPOOPRM1BRD4ALDH1A1 | |
| SCHEMBL6690334 | 0.68 | RXFP1 (0.40) | RXFP1LMNAALDH1A1KDM4EGAA | |
| SCHEMBL5033267 | 0.67 | GPR3 (0.52) | LMNAALDH1A1KDM4EGAAPDE2A | |
| SCHEMBL10957749 | 0.66 | CSNK2A2 (0.43) | RXFP1OPRM1ALDH1A1KDM4EGAA | |
| SCHEMBL13384603 | 0.66 | ATAD2 (0.41) | BRD4LMNATAF1BRPF1CREBBP | |
| SCHEMBL14191781 | 0.65 | BRD4 (0.33) | BRD4TAF1BRPF1CREBBPCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168309-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | INVOX PHARMA LIMITED (GB) | 2022-06-02 | — | — | US | disclosed |
| EP-3180342-A1 | PYRROLO[3,2-D]PYRIMIDINE-2,4(3H,5H)-DIONE DERIVATIVES | Hydra Biosciences, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016023831-A1 | PYRROLO[3,2-D]PYRIMIDINE-2,4(3H,5H)-DIONE DERIVATIVES | HYDRA BIOSCIENCES, INC. (US) | 2016-02-18 | — | — | WO | disclosed |
| WO-2004067006-A1 | COMBINATION OF A PDE IV INHIBITOR AND A TNF-ALPHA ANTAGONIST | PHARMACIA CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168309-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | STING1, CGAS, MAVS | RXFP1 888/4885MPO 794/4885OPRM1 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.